Glossary Terms

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C

caBIG™

The cancer Biomedical Informatics Grid, or caBIG™, is the network or grid connecting individuals and institutions involved with cancer research to enable them to share data and computer tools. caBIG™ is an initiative supported by the National Cancer Institute, National Institutes of Health.

Chromosomal Rearrangements

Structural alterations in the native structure of a chromosome resulting from the breakage and rejoining of two separate parts of a chromosome.

Chromosome

One of the threadlike "packages" of genes located in the nucleus of a cell. Humans have 23 pairs: 46 chromosomes; 44 autosomes, and an X and Y chromosome.

Chromosome Translocation

Breakage and removal of a large segment of DNA from one chromosome, followed by the segment's attachment to a different chromosome.

Clinical Candidates

Drugs that are being tested in clinical trials but are not yet approved by the Food and Drug Administration.

Complete Response

The disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured. Also called complete remission.

Cytogenetics

The analyses of chromosomal  number and structure.