Data Access

The goal of the Office of Cancer Genomics (OCG) is to accelerate translation of basic science discoveries into the clinic and thereby contribute to precision oncology. OCG collaboratively manages and supports molecular characterization and translational genomics research initiatives: Cancer Genome Characterization Initiative (CGCI); Therapeutically Applicable Research to Generate Effective Treatments (TARGET); Cancer Target Discovery and Development (CTD2) Network; Human Cancer Models Initiative (HCMI); and Next Generation Technologies for Next Generation Cancer Models (NGT). OCG programs produce and share large-scale genomic datasets as “community resource projects”. The data generated by these programs are disseminated to the research community in accordance with National Institute of Health’s data sharing policies via program-specific databases (data matrices, data portals, and dashboard) and through the Genomic Data Commons (GDC).

Access OCG programs’ data and read the accompanying user guides in the table below:

OCG Program

Data Description

Data Links

User Guides

CGCI and TARGET

Genomic profiles (molecular characterization and other sequencing data) and clinical data for rare adult and pediatric cancers. CGCI and TARGET datasets may be open-access or controlled-access (which requires approval by NCI Data Access Committee (DAC)).

CGCI Data Matrix

 

CGCI Data at GDC

CGCI Publication Guidelines

TARGET Data Matrix

 

TARGET Data at GDC

TARGET Publication Guidelines

CTD2

Raw and analyzed primary data are available through the CTD2 Data Portal. CTD2 data are mostly open-access.

CTD2 Data Portal

 

 

Using CTD2 Data

 

CTD2 Publication Guidelines

The CTD2 Dashboard is a web interface which assembles Network Center-generated conclusions or “observations” with associated supporting evidence. The Dashboard allows easy navigation to biologists and data scientists.

CTD2 Dashboard

HCMI

The quality-controlled and harmonized clinical, biospecimen, and molecular characterization data are available at NCI’s GDC. HCMI datasets may be open-access or controlled-access (which requires approval by NCI Data Access Committee (DAC)).

HCMI Data at GDC

HCMI Publication Guidelines

 

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