News & Publications

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Tang et al. (2021) STAR Protocols. CC BY-NC-ND 4.0
STAR Protocols

Protein-protein interactions (PPIs) have emerged as promising yet challenging therapeutic targets. A robust bioassay is required for rapid PPI modulator discovery. Here, we present a time-resolved Förster's (fluorescence) resonance energy transfer assay protocol for PPI modulator screening in a...

Dai et al. (2021) Cell Rep. CC BY-NC-ND 4.0
Cell Reports

Metastasis is a complex and poorly understood process. In pancreatic cancer, loss of the transforming growth factor (TGF)-β/BMP effector SMAD4 is correlated with changes in altered histopathological transitions, metastatic disease, and poor prognosis. In this study, we use isogenic cancer cell...


Issue 25, February, 2021

CTD² Program Highlights

Cancer Target Discovery and Development Logo
Kenneth Smith, Ph.D., Vlado Dancik, Ph.D., Zhou Ji, Ph.D., Aristidis Floratos, Ph.D., and Paul Clemons, Ph.D.
Last updated: October 04, 2021