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In the News


Small-molecule screen in drug-tolerant persister cells

Acquired drug resistance prevents cancer therapies from achieving stable and complete responses. Emerging evidence implicates a key role for non-mutational drug resistance mechanisms underlying the survival of residual cancer 'persister' cells. The persister cell pool constitutes a reservoir...

Clustering of miRNA expression profiles from primary AML
Journal of Clinical Oncology

Children with acute myeloid leukemia (AML) whose disease is refractory to standard induction chemotherapy therapy or who experience relapse after initial response have dismal outcomes. We sought to comprehensively profile pediatric AML microRNA (miRNA) samples to identify dysregulated genes and...


Issue 16, July, 2017

CTD² Program Highlight

Cancer Target Discovery and Development
Subhashini Jagu, Ph.D. and Daniela S. Gerhard, Ph.D.
Last updated: May 15, 2013