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In the News


PPI maps cancer genes like MYC, STK11,RASSF1 and CDK4
Nature Communications

As genomics advances reveal the cancer gene landscape, a daunting task is to understand how these genes contribute to dysregulated oncogenic pathways. Integration of cancer genes into networks offers opportunities to reveal protein–protein interactions (PPIs) with functional and therapeutic...

Predicted beta catenin interacting proteins.
PLoS One

Protein-protein interactions (PPIs) mediate the transmission and regulation of oncogenic signals that are essential to cellular proliferation and survival, and thus represent potential targets for anti-cancer therapeutic discovery. Despite their significance, there is no method to experimentally...


Issue 15, October, 2016

OCG Perspective

Nadia Jaber
Last updated: May 15, 2013