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All Programs

Poster Presentation at Virtual AACR Annual Meeting 2021

June 04, 2021

TARGET

Working Towards Greater Precision in Childhood Cancers

March 07, 2018

HCMI

Office of Cancer Genomics launches new program

July 11, 2016

Publications

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CTD²

Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma

Cancer Cell.

Checkpoint inhibition immunotherapy has revolutionized cancer treatment, but many patients show resistance. Here we perform integrative transcriptomic and proteomic analyses on emerging immuno-oncology targets across multiple clinical cohorts of melanoma under anti-PD-1 treatment, on both bulk...

CTD²

Secondary fusion proteins as a mechanism of BCR::ABL1 kinase-independent resistance in chronic myeloid leukaemia

Br J Haematol.

Drug resistance in chronic myeloid leukaemia (CML) may occur via mutations in the causative BCR::ABL1 fusion or BCR::ABL1-independent mechanisms. We analysed 48 patients with BCR::ABL1-independent resistance for the presence of secondary fusion genes by RNA sequencing. We identified 10 of the...

Last updated: November 08, 2022