News & Publications

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Publications

Graphical abstract from Chun, et al (2019).
TARGET
Cell Reports

Extra-cranial malignant rhabdoid tumors (MRTs) and cranial atypical teratoid RTs (ATRTs) are heterogeneous pediatric cancers driven primarily by SMARCB1 loss. To understand the genome-wide molecular relationships between MRTs and ATRTs, we analyze multi-omics data from 140 MRTs and 161 ATRTs. We...

The RET, RAS-RAF-MAPK pathway with sites of RXDX-105 inhibition in red.
CTD²
Oncotarget

Neuroblastoma is the most common extracranial solid tumor of childhood and accounts for 15% of all pediatric cancer-related deaths. New therapies are needed to improve outcomes for children with high-risk and relapsed tumors. Inhibitors of the RET kinase and the RAS-MAPK pathway have previously...

e-Newsletter

Issue 23, December, 2019

CTD² Guest Editorial

Aaron T. Griffin, M.D. Ph.D. program, Prabhjot S. Mundi, M.D., and Andrea Califano, Ph.D.
Aaron T. Griffin, M.D. Ph.D. program, Prabhjot S. Mundi, M.D., and Andrea Califano, Ph.D.
Last updated: December 10, 2019