Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.

* denotes publications from the CTD2 initiative that are results of intra-Network collaborations


September 04, 2018
Scientific Reports

High-throughput functional siRNA screening in ovarian cancer cell lines identified that tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE-1 confers resistance to cisplatin and could be a potential therapeutic target for platinum resistant ovarian cancer. 

September 01, 2018

Studies conducted by CTD2 scientists at Oregon Health and Science University have shown that combined inhibition of JAK1/2 and BCL2 as a potential therapeutic option for acute myeloid leukemia (AML) patients.

August 13, 2018
Nature Cell Biology

CTD2 researchers at UCSF showed that SHP2, a non-receptor protein tyrosine phosphatase, could be a potential molecular target in cancers driven by oncogenic mutants of RAS/MAPK pathway.

August 13, 2018
Journal of Clinical Pathology

Review on the role of CDK12 as a clinical biomarker and as a potential therapeutic target for cancer therapy.

August 08, 2018
Trends in Cancer

A review article on using the patient-derived cancer models for the identification of targets to overcome roadblocks of precision oncology.

August 01, 2018
Cold Spring Harbor Perspectives in Medicine
July 30, 2018

Genome-scale open reading frame screen identifies RNA binding proteins, QK1 and RBFOX1, regulate the alternate splicing of actin binding protein, FLNB. The skipping of FLNB exon 30 is associated with the transition to mesenchymal- and stem-like cell states in breast cancer pathogenesis.