Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.

* denotes publications from the CTD2 initiative that are results of intra-Network collaborations


May 12, 2014
Cancer Cell

Cross-species computational analysis of interactomes from mouse models and human prostate cancer identified FOXM1 and CENPF as synergystic master regulators of prostate malignancy/tumor growth.

May 08, 2014
Nature Communcations

Using a high-coverage genome-wide shRNA library, researchers identify the characterized protein TMEM129 and the ubiquitin-conjugated E2 enzyme UBE2J2 to be essential for US11-mediated HLA class I downregulation.

April 23, 2014
Journal of Natural Products

Researchers describe toxicity of three new acylated arylamine derivatives (1-3), carpatamides A-C against non-small-cell lung cancer cell lines HCC366, A549, and HCC44.

April 23, 2014
Nature Communications

Researchers show that squamous cell carcinoma antigens 1 and 2 (SCCA1/2), members of the Serpin family of serine/cysteine protease inhibitors, are transcriptionally upregulated by oncogenic Ras via MAPK and the ETS family transcription factor PEA3.

April 17, 2014

A web-based tool for exploring genomic vulnerabilities in cancer is available at

April 16, 2014
PLoS One

In this publication, the authors describe the generation of two mouse strains that enable Cre-dependent, robust expression of  reverse tet-transactivator 3, providing tissue-restricted and consistent induction of TRE-controlled transgenes.

April 14, 2014
Human Pathology

Researchers discuss identify somatic mutations with archival formalin fixed and paraffin embedded tissue from gallbladder cancer.

April 07, 2014

This work identifies nuclear PRAS40 as a dual-input signaling checkpoint that links cell growth and proliferation to inhibition of cellular senescence. 

April 01, 2014
Nucleic Acids Research

This manuscript presents a method called Evaluation of Dependency DifferentialitY (EDDY), which is a statistical test for differential dependencies of a set of genes between two conditions.

March 13, 2014
Comb Chem High Throughput Screen

Researchers at Emory disucss their high throughput research platforms and efforts to advance understanding of disease-related biology with its HTS/HCS platforms and chemical tools, in support of  drug discovery.