Publications

Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.

* denotes publications from the CTD2 initiative that are results of intra-Network collaborations

 

CTD²
March 01, 2014
Nature Reviews Clinical Oncology

A review of how a systems biology approach to cancer research can effect therapy development.

CTD²
March 01, 2014
Cold Spring Harbor Perspective in Medicine

Researchers screen for synthetic lethal interactions with MYC to identify possible routes for therapy.

CTD²
March 01, 2014
Nature Medicine

Researchers identify ARID1A-mutant cancer cells are dependent on ARID1B for survival, suggesting a potential therapeutic target.

CTD²
March 01, 2014
Cancer Discovery

Investigators used a novel mouse model to study genetic changes in prostate cancer.

CTD²
January 30, 2014
Cell Reports

The authors performed an image-based screen for genes regulating glioblastoma tumor-initiating cell maintenance and identified the transcription factor, ZFHX4, as a master regulator.

CTD²
January 21, 2014
Proceedings of the National Academy of Sciences

The researchers identified the GRB2-associated binding protein 2 (GAB2) as a recurrently amplified gene that potently transforms immortalized ovarian and fallopian tube secretory epithelial cells. 

CTD²
January 16, 2014
Cell

Glutathione peroxidase 4 regulates ferroptotic cancer cell death.

CTD²
January 15, 2014
Clinical Cancer Research

Investigators identified molecular players in response and resistance to combination chemotherapy and antiangiogenic drugs.

CTD²
January 13, 2014
Molecular and Cell Biology

Researchers discuss a role for SMARCA2 in oncogenesis caused by SMARCA4 loss and identify the ATPase and bromodomain-containing SMARCA2 as a potential therapeutic target in these cancers.

CTD²
January 02, 2014
Bioinformatics

Researchers discuss quantitative solution to overcorrection and guidance for effective designs of deep sequencing platforms that facilitate accurate estimation of variant allele fraction and copy number variation.

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