Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.
* denotes publications from the CTD2 initiative that are results of intra-Network collaborations
Researchers at Emory disucss their high throughput research platforms and efforts to advance understanding of disease-related biology with its HTS/HCS platforms and chemical tools, in support of drug discovery.
A review of how a systems biology approach to cancer research can effect therapy development.
Researchers screen for synthetic lethal interactions with MYC to identify possible routes for therapy.
Researchers identify ARID1A-mutant cancer cells are dependent on ARID1B for survival, suggesting a potential therapeutic target.
Investigators used a novel mouse model to study genetic changes in prostate cancer.
The authors performed an image-based screen for genes regulating glioblastoma tumor-initiating cell maintenance and identified the transcription factor, ZFHX4, as a master regulator.
The researchers identified the GRB2-associated binding protein 2 (GAB2) as a recurrently amplified gene that potently transforms immortalized ovarian and fallopian tube secretory epithelial cells.
Glutathione peroxidase 4 regulates ferroptotic cancer cell death.
Investigators identified molecular players in response and resistance to combination chemotherapy and antiangiogenic drugs.
Researchers discuss a role for SMARCA2 in oncogenesis caused by SMARCA4 loss and identify the ATPase and bromodomain-containing SMARCA2 as a potential therapeutic target in these cancers.