Publications

Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.

* denotes publications from the CTD2 initiative that are results of intra-Network collaborations

 

CTD²
July 17, 2018
Cell

Researchers at UCSF developed an analytical framework for constructing a human genetic interaction map, a powerful tool to identify genetic interactions between genes and suggest new combination therapies for cancer.

CTD²
July 16, 2018
Nature Communications

In vivo gain-of-function genetic screen identifies TMEMB, a transmembrane protein as a novel driver of invasion and metastasis in lung cancer.

CTD²
July 16, 2018
Nature Communications

In vivo functional screening identifies transcriptional repressor, GATAD2B, as a potent driver of tumor growth and metastasis in KRAS-mutant lung cancer through interaction with c-Myc.

CTD²
July 01, 2018
Nature Genetics

Integration of comprehensive molecular characterization and functional genomic studies identifies paralog gene dependencies induced by somatic mutations. Paralog pair, MAGOH and MAGOHB, identified as members of the exon-junction complex was shared between the shRNA and CRISPR datasets.

CTD²
June 28, 2018
Cell Stem Cell

Natural killer cells derived from human-induced pluripotent stem cells are effective against ovarian cancer in a mouse xenograft model and may provide an off-the-shelf resource for anti-cancer immunotherapy.

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