Publications
Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.
* denotes publications from the CTD2 initiative that are results of intra-Network collaborations
TCGA researchers identified four distinct molecular subtypes of glioblastoma multiforme (GBM), and demonstrated that response to aggressive chemotherapy and radiation differed by subtype.
CGEMS researchers announce discovery of new area on chromosome 8 that is associated with risk for prostate cancer.
The MGC Project Team announces the completion of the Mammalian Gene Collection.
Researchers identified a poor prognostic subgroup of pediatric BCR-ABL1-negative ALL patients and reported that the JAK-mutated cases had a gene expression signature similar to BCR-ABL1 pediatric ALL and suggested inhibition of JAK signaling as a target for therapeutic intervention.
CGEMS Researchers have identified new genetic variations in two regions of DNA — located on chromosomes 1 and 14 — that may be associated with the risk of sporadic breast cancer.
Scientists identified more than 50 recurring copy-number abnormalities in a cohort of patients with B-cell progenitor ALL. Abnormalities were found in genes that encode regulators of B-cell development, PAX5 and IKZF1, a gene that encodes the lymphoid transcription factor IKAROS.
The Cancer Genome Atlas Research Network reported the first results of its large-scale, comprehensive study of the most common form of brain cancer, glioblastoma (GBM) in the advance online edition of the journal Nature, released September 4, 2008.
The prostate cancer study looks at the association between multiple loci and the susceptibility to prostate cancer, which could be used as an indicator for high risk individuals (subscription required).
The Initiative for Chemical Genetics (ICG), created by NCI, enables public research using small molecules to accelerate the discovery of cancer-relevant small-molecule probes.
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