Publications

Included here is a list of publications from OCG programs. All published data are available to the research community through the program-specific data matrices.

* denotes publications from the CTD2 initiative that are results of intra-Network collaborations

 

CTD²
June 25, 2018
Nature Chemical Biology

UCSF (1) CTD2 scientists developed a quantitative chemoproteomics approach that combines kinase affinity capture with quantitative mass spectrometry. This technique could be used for developing effective combinatorial therapies.

CTD²
June 18, 2018
Nature Genetics

CTD2 sceintists at Columbia University developed a new precision oncology approach, OncoTreat. This approach enables the systematic prioritization of compounds targeting tumor checkpoint dependencies in gastroenteropancreatic neuroendocrine tumors.

CTD²
TARGET
June 07, 2018
Oncogene

Authors identified transcription factor activating protein 4 (TFAP4) as a critical effector of MYCN amplification in neuroblastoma and showed that silencing TFAP4 inhibits MYCN-amplified neuroblastoma cell growth. 

CTD²
June 01, 2018
Nature Cell Biology

CTD2 scientists at UCSF showed that tumor progression and dissemination are governed by evolutionary selection pressures that operate at a multicellular level and differ from the clonal events that drive initiation and the benign-malignant transition.

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