Percentage of genes in the human genome represented in the ORFeome collection, separated into functional categories. Reprinted by permission from Macmillan Publishers Ltd: Nature Methods (ORFeome Collaboration (2016). The ORFeome Collaboration: a genome-scale human ORF-clone resource. Nat Methods 13(3):191-2), copyright (2016).
The ORFeome Collaboration (OC) is a team of academic and commercial entities which have generated the largest collection of clones containing verified open-reading frames (ORFs) of known human genes. The clones are made available to researchers worldwide through multiple distributors. This valuable resource allows researchers to easily express and study human genes. The OC recently published in Nature Methods that the ORFeome collection now covers nearly 80% of all protein-coding genes in the human genome. As the ORFeome continues to grow, so too will its uses in the research world. For more information and updates to the OC, visit the OC website (link below)