623 Publications Available
August 15, 2012
Science Translational Medicine

The comprehensive characterization of a large number of cancer genomes will eventually lead to a compendium of genetic alterations in specific cancers.

August 10, 2012

Researchers describe emerging approaches that aim to determine which altered genes are actually contributing to cancer, as well as their potential as therapeutic targets.

July 19, 2012

Investigators screemed a library of kinases that lead to activation of the MAPK pathway and identified PAK1.

April 15, 2012
Genes and Development

Glioblastoma is both the most common and lethal primary malignant brain tumor.

October 05, 2011
Sci Trans Med.

The fusion of empirical science with large-scale computing platforms has allowed rapid advances in our ability to model physiological and pathophysiological processes in silico.

July 26, 2011
Proceedings of the National Academy of Sciences

A comprehensive understanding of the molecular vulnerabilities of every type of cancer will provide a powerful roadmap to guide therapeutic approaches.

July 13, 2011

The authors introduce a small molecule to induce apoptosis selectively in cancer cells.

April 08, 2011
Genes and Development

High-throughput tools for nucleic acid characterization now provide the means to conduct comprehensive analyses of all somatic alterations in the cancer genomes.