613 Publications Available
March 13, 2014
Comb Chem High Throughput Screen

Researchers at Emory disucss their high throughput research platforms and efforts to advance understanding of disease-related biology with its HTS/HCS platforms and chemical tools, in support of  drug discovery.

March 01, 2014
Cold Spring Harbor Perspective in Medicine

Researchers screen for synthetic lethal interactions with MYC to identify possible routes for therapy.

March 01, 2014
Cancer Discovery

Investigators used a novel mouse model to study genetic changes in prostate cancer.

March 01, 2014
Nature Reviews Clinical Oncology

A review of how a systems biology approach to cancer research can effect therapy development.

March 01, 2014
Nature Medicine

Researchers identify ARID1A-mutant cancer cells are dependent on ARID1B for survival, suggesting a potential therapeutic target.

January 30, 2014
Cell Reports

The authors performed an image-based screen for genes regulating glioblastoma tumor-initiating cell maintenance and identified the transcription factor, ZFHX4, as a master regulator.

January 21, 2014
Proceedings of the National Academy of Sciences

The researchers identified the GRB2-associated binding protein 2 (GAB2) as a recurrently amplified gene that potently transforms immortalized ovarian and fallopian tube secretory epithelial cells. 

January 16, 2014

Glutathione peroxidase 4 regulates ferroptotic cancer cell death.

January 15, 2014
Clinical Cancer Research

Investigators identified molecular players in response and resistance to combination chemotherapy and antiangiogenic drugs.

January 13, 2014
Molecular and Cell Biology

Researchers discuss a role for SMARCA2 in oncogenesis caused by SMARCA4 loss and identify the ATPase and bromodomain-containing SMARCA2 as a potential therapeutic target in these cancers.