Publications

613 Publications Available
October 14, 2013
Cancer Cell

Researchers document coexpression of EGFR and EGFRvIII in primary human glioblastoma that drives transformation and tumorigenesis in a cell-intrinsic manner and clarify specific oncogenic signaling relationships in glioblastoma.

October 04, 2013
Clinical Cancer Research

Author comment on Dual blockade of the PI3K/AKT/mTOR(AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergystically inhibits rhabdomyosarcoma... 

October 01, 2013
Cold Spring Harbor Perspective in Medicine

A review on the role of MYCN and other newly identifed drivers in neuroblastoma.

October 01, 2013
Nature Genetics

A collaborative effort to compare the molecular changes across the original 12 tumor types profiled by The Cancer Genome Atlas.

September 11, 2013
Journal of the American Chemical Society

Using a newly developed platform to identify the signaling pathway/molecular target of natural products, we identified a family of alkaloid natural products, discoipyrroles A-D (1-4), from Bacillus hunanensis that inhibit the DDR2 signaling pathway. 

September 01, 2013
Cancer Discovery

3q26 is frequently amplified in several cancer types with a common amplified region containing 20 genes. To identify cancer driver genes in this region, we interrogated the function of each of these genes.

August 29, 2013
Cell

The Cancer Therapeutics Response Portal (www.broadinstitute.org/ctrp) was created to identify cancer genotype-compound sensitivity relationships.

August 15, 2013
Bioinformatics

Researchers introduce the PiHelper, which integrates human drug-target and antibody-target associations from publicly available resources to help meet the needs of researchers in systems pharmacology, perturbation biology and proteomics.

August 05, 2013
Oncogene

Using nanofluidic proteomic immunoassay researchers demonstrate that under basal and ligand-induced conditions that the pattern of phosphorylation events is markedly different between AKT1 and AKT2.

Pages

CSVJSON

.