556 Publications Available
October 23, 2013
PLoS One

Researchers present a cancer driver annotation (CanDrA) tool that predicts missense driver mutations based on a set of 95 structural and evolutionary features computed by over 10 functional prediction algorithms.

October 15, 2013
Science Signaling

Researchers accrued a library of natural products and performed a screen to identify molecular targets.

October 15, 2013
Cancer Research

Investigators use a high-throughput assay to identify genomic predictors of radiation sensitivity

October 14, 2013
Cancer Cell

Researchers document coexpression of EGFR and EGFRvIII in primary human glioblastoma that drives transformation and tumorigenesis in a cell-intrinsic manner and clarify specific oncogenic signaling relationships in glioblastoma.

October 04, 2013
Clinical Cancer Research

Author comment on Dual blockade of the PI3K/AKT/mTOR(AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergystically inhibits rhabdomyosarcoma... 

October 01, 2013
Cold Spring Harbor Perspective in Medicine

A review on the role of MYCN and other newly identifed drivers in neuroblastoma.

October 01, 2013
Nature Genetics

A collaborative effort to compare the molecular changes across the original 12 tumor types profiled by The Cancer Genome Atlas.

September 11, 2013
Journal of the American Chemical Society

Using a newly developed platform to identify the signaling pathway/molecular target of natural products, we identified a family of alkaloid natural products, discoipyrroles A-D (1-4), from Bacillus hunanensis that inhibit the DDR2 signaling pathway. 

September 01, 2013
Cancer Discovery

3q26 is frequently amplified in several cancer types with a common amplified region containing 20 genes. To identify cancer driver genes in this region, we interrogated the function of each of these genes.