599 Publications Available
April 15, 2012
Genes and Development

Glioblastoma is both the most common and lethal primary malignant brain tumor.

October 05, 2011
Sci Trans Med.

The fusion of empirical science with large-scale computing platforms has allowed rapid advances in our ability to model physiological and pathophysiological processes in silico.

July 26, 2011
Proceedings of the National Academy of Sciences

A comprehensive understanding of the molecular vulnerabilities of every type of cancer will provide a powerful roadmap to guide therapeutic approaches.

July 13, 2011

The authors introduce a small molecule to induce apoptosis selectively in cancer cells.

April 08, 2011
Genes and Development

High-throughput tools for nucleic acid characterization now provide the means to conduct comprehensive analyses of all somatic alterations in the cancer genomes.

March 08, 2011
Cancer Cell

The authors screened 124 genes that are amplified in human hepatocellular carcinoma (HCC) using a mouse hepatoblast model and identified 18 tumor-promoting genes, including CCND1 and its neighbor on 11q13.3, FGF19.

September 01, 2010
Nature Biotechnology

Genomic analysis of primary tumors is providing extraordinary insights into the molecular changes in genes and pathways that cause cancer.

January 21, 2010

Researchers discover that two transcription factors C/EBPbeta and STAT3 are responsible for mesenchymal transformation in glioma.