OCG Templates and Protocols

The OCG Standard Operating Protocols (SOPs) and templates are guidelines for investigators participating in OCG programs such as CGCI's Burkitt Lymphoma Genome Sequencing Project (BLGSP), and HIV+ Tumor Molecular Characterization Project (HTMCP), the Human Cancer Models Initiative (HCMI), and Therapeutically Applicable Research To Generate Effective Treatments (TARGET). Investigators must follow the protocols in the SOPs when contributing samples and data. The sample and data acquisition process is explained in comprehensive detail to ensure that all materials and data will be of sufficient quality. Depending on the role in the acquisition process, only a certain number of protocols may apply to a particular investigator. Should you require any clarification, please contact the appropriate OCG personnel listed in the SOP.

Burkitt Lymphoma Genome Sequencing Project (BLGSP) SOP Manual

Characteristics of Successful Standard Operating Procedures (SOPs)

HIV+ Tumor Molecular Characterization Project (HTMCP) SOP Manual

Human Cancer Models Initiative Case Report Forms (CRFs)

In an effort to advance cancer research and more fully understand how in vitro findings are related to clinical biology, HCMI next-generation cancer models are associated with clinical data. Clinical Data Working Groups, composed of clinical experts from the HCMI member states, have contributed to the composition of the CRFs used to collect HCMI clinical data. Enrollment and Follow-up CRFs that have been developed are available below for download. As the tumor types modeled through the HCMI are constantly updated, be sure to check back regularly for additional CRFs.

Enrollment CRFs
Follow-up CRFs

Informed Consent Template for Model Development and Distribution

TARGET Project Experimental Methods

On this page researchers can find detailed information describing how TARGET data was generated by genomic platform, including protocols for establishing high-quality nucleic acid samples.